Sixteen-year-old Simon Spier quietly enjoys flirtatious emails between himself and a guy calling himself "Blue," hoping it will lead to a relationship. However, the emails fall into the wrong hands and Simon is blackmailed. Now Simon must explore his feelings and decide if being outed to the rest of the high school is such a bad thing.

Seventeen-year-old Molly Peskin-Suso has had a total of twenty-six crushes and precisely zero kisses, and her twin sister, Cassie, is lesbian. When Cassie starts dating a new girlfriend, the pansexual Korean American Mina, Molly finds herself drawn to Mina's cute hipster male sidekick, Will. Molly hopes dating Will might help heal the division between her and her twin, but when she becomes more attracted to Reid, a geeky, chubby coworker, she worries...