Detective John Hobbes is searching for a criminal he's already met, already caught and already killed.

FBI Agent Will Graham hunts the most notorious serial killers. He is both gifted and cursed with an extraordinary ability: he can think, see, and feel like his prey. What he doesn't know is that his new partner has an extreme past. While pursuing a cannibalistic murderer, Special Agent Jack Crawford teams Graham with a psychiatrist, Dr. Hannibal Lecter. Dr. Lecter tests Graham every step of the way, playing a game all his own, while they work to unravel...

Illeana Scott is a special agent with the FBI, who has a strong record as a criminal profiler. Scott is called in by a former Quantico colleague to assist two Canadian police detectives, Paquette and Duval, who are on the trail of a serial killer who has been killing in and around Montreal for almost two decades. Art gallery owner James Costa saw the killer during an assault, and now finds himself working as a decoy for Scott. As Scott and Costa follow...

When a young woman goes missing at a truck stop along I-50, an FBI agent and a Texas Ranger team up for an unauthorized investigation to find her before she becomes the latest victim of an elusive serial killer.

Detective Jessica Sheppard is on the prowl for a serial killer whose victims have one thing in common - her. Suffering from a series of bizarre blackouts, Sheppard must uncover the killer before her partner pins her as the prime suspect.

Turk and Rooster are two aging NYPD detectives who have been partners for 30 years. They are faced with a serial killer who is murdering other sociopathic criminals. They both have personal issues. They start working with Perez and Riley, a younger team. Tensions between the pairs of partners is inevitable, especially since Turk is now living with Perez's ex-girlfriend. She also happens to be a homicide detective. But before Turk and Rooster can retire,...

Will Graham is an FBI agent who brought Hannibal Lecter to justice; however, his confrontation with Lecter proved to be a bloody, near-death experience. Retiring from the Bureau, he moves to Florida. However, a particularly grisly killer is on the loose, and Jack, Graham's one-time mentor at the Bureau, asks him to return to duty to find him. "The Tooth Fairy" is a vicious murderer who kills entire families at once, covering the eyes of his victims...

When he was 9 years old, Tim and his mother were abducted by taxi-driving serial killer Bob. Tim's mother was murdered. Tim was kept as a chained slave, forced to bury the bodies of young women Bob drags home and keep scrapbooks of the crimes. Now a teenager, Tim and Bob share a depraved father/son/protege relationship. But who will ultimately sever the bond between family and unimaginable horror?

Host Robert Stack investigates the most shocking and mysterious stories of our time. Disc 4 includes 9 episodes plus bonus features.